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Making Baby Series - Part 20 : Caffeine, Coffee, and Alcohol



LIMIT CAFFEINE AND COFFEE
Caffeine can decrease the flow of blood to the uterus, which can interfere with implantation. Too much caffeine may increase the risk of clotting and miscarriage.
Caffeine can also increase stress and anxiety levels. Studies on caffeine and fertility in general are inconclusive, but you’ll do best to avoid it if blood flow or implantation problems or miscarriage is your main fertility issue. Some fertility types are more prone to negative effects of caffeine than others (see part V), but for almost everyone, up to 90 mg a day is generally safe. That’s the equivalent of about one cup of regular brewed coffee, two cups of black tea, or three cups of green tea. The caffeine in colas and chocolate counts, too.




It’s best to limit coffee, whether it’s regular or decaf. Coffee is acidic and can make the body and the cervical mucus acidic, too. Several studies have concluded that coffee (with or without caffeine) diminishes fertility. A recent large Dutch study determined that four cups of coffee a day lowered a woman’s chances of having a baby by more than 25 percent—comparable to the fertility damage done by smoking, being overweight, or having three or more alcoholic drinks a week. Some studies have linked coffee and miscarriage, and some have linked coffee and low sperm count. But not all studies have found a problem with coffee. So as with most things, we recommend moderation. If you drink a lot of coffee, cutting back may be a good idea, perhaps to just one cup in the morning. (We’re talking about a normal six- to eight-ounce cup, not the huge super-grande “to go” cups that everyone seems to be carrying around these days.) Many of our patients have made the switch from coffee to tea, and that’s another good option. If you find you are having fertility problems, you may want to eliminate coffee altogether.

AVOID ALCOHOL
Many women avoid alcohol while trying to conceive, on the theory that since they won’t drink at all while pregnant, they shouldn’t drink at any time when they might be pregnant. But being cautious about alcohol while trying to conceive is not just about potential effects on the fetus. Alcohol affects fertility, too.
The research on this subject is something of a mixed bag. Some studies have found no link between moderate drinking and fertility issues. But some show that even low levels of alcohol can cut fertility by as much as one-half. For example, one large study concluded that women who had fewer than five drinks a week were twice as likely to get pregnant in a given six-month period compared to women who drank more. Another study demonstrated that men who drank alcohol regularly took twice as long to get their partners pregnant as men who didn’t drink at all. In both sexes, the more alcohol consumed, the less likely conception is. Most studies agree: high alcohol intake significantly impairs fertility.

Alcohol is one of the most common factors affecting fertility in men. It is toxic to sperm, and overuse can reduce sperm quality, increase abnormal sperm, and lower motility. Men who drink have been shown to have lower sperm counts and lower testosterone than teetotalers, as well as decreased libido and increased risk of erectile dysfunction (ED). In women, alcohol can be a risk factor for ovulatory infertility.

Drinking alcoholic beverages has also been shown to decrease the success rates of ARTs, including IVF. According to one study of couples undergoing IVF, women who had one drink more per day than others tripled their risk of not getting pregnant in any given cycle and more than doubled their risk of miscarriage. When it was the man who had that extra daily drink, the risk of miscarriage was between two and thirty-eight times greater, depending on the timing of the drinking in relation to the IVF cycle. One month before IVF and during IVF were the most hazardous times.
Besides its direct effects, alcohol also interferes with the body’s ability to absorb nutrients from food. That includes zinc, which is key for male fertility in particular. Alcohol interferes with the action of folic acid as well, which plays an important role in the maturation of an egg for ovulation. Finally, alcohol acidifies the body, including the cervical mucus. If the mucus gets too acidic, sperm can’t survive in it, and so can’t reach the egg.


What You Can Do About It
Most people will need to moderate their alcohol intake, and some will need to cut back substantially or eliminate it altogether. Some women actually benefit from a glass of wine or beer now and then. In general, women should have no more than one small glass of wine or beer per day, and men no more than two small glasses or one mixed drink. For most people it’s best not to have a daily drink while you’re trying to conceive; reserve drinking for social occasions. See part V for specific advice about alcohol consumption tailored to your individual fertility type.


Case Study: Annie and Kevin 
By the time Annie and Kevin came to see me (Jill), they had been through one unsuccessful IVF and one IVF that had ended in miscarriage due to chromosomal abnormality. Annie seemed quite healthy to me, and I could see no good reason why she was unable to conceive. 

She told me that her husband, Kevin, had been diagnosed with poor sperm motility and morphology, but the doctors had reassured them that although this may have been the reason they couldn’t conceive naturally, it shouldn’t get in the way of IVF. I thought a session with Kevin would be in order.

 In my office, he said that he guessed he drank rather a lot of alcohol, unwinding in the evening after stressful workdays with a gin and tonic and a couple of glasses of wine. He said that he would cut that out if I thought it would help, and he would overhaul his diet while he was at it. Five months later, he had a perfect semen analysis, and they immediately scheduled another round of IVF—with healthy sperm this time—for the next month. Annie and Kevin are now the proud parents of a healthy baby girl.
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